What are the toxic causes of pulmonary veno-occlusive disease (PVOD)?

Updated: Oct 16, 2018
  • Author: Hakim Azfar Ali, MD; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Answer

PVOD has been reported after the administration of various chemotherapeutic agents such as bleomycin, mitomycin, and carmustine (BCNU), similar to hepatic veno-occlusive disease. [20, 21] Other chemical exposures that have been linked to the development of PVOD include powdered cleaning products containing silica, soda ash, dodecyl benzyl sulfonate, and trichloro-s-triazinetrione. [22] PVOD seems to occur more commonly in bone marrow transplant recipients than in the general population. [23, 24]


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