What is the role of stem cell transplantation (SCT) in the treatment of primary refractory Burkitt lymphoma/Burkitt-like lymphoma (BL/BLL)?

Updated: Dec 20, 2019
  • Author: Ali H Kanbar, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Patients with primary refractory disease do not respond well to high-dose chemotherapy plus autologous SCT. The duration of responses in these patients is often short, with eventual relapse in most reported series. Alternative approaches, including allogeneic SCT/bone marrow transplantation or salvage regimens in the setting of a clinical trial, should be considered in these cases. [6, 64]


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