How is response to chemotherapy evaluated in patients with Burkitt lymphoma/Burkitt-like lymphoma (BL/BLL)?

Updated: Dec 20, 2019
  • Author: Ali H Kanbar, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

After completion of chemotherapy, the response to treatment should be investigated. This should include patient history, physical examination, laboratory studies (complete blood cell (CBC) count, renal/liver profiles, and lactate dehydrogenase [LDH] levels) ,and posttherapy imaging, preferably computed tomography (CT) scans (see Workup).

A complete remission is achieved if the patient has no evidence of disease or disease-related symptoms and if all the masses or lymph nodes that were previously present have resolved on the posttreatment CT scan. If the bone marrow was involved before treatment, a repeat bone marrow biopsy should be normal.


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