What are the most common clinical findings for Burkitt lymphoma/Burkitt-like lymphoma (BL/BLL)?

Updated: Dec 20, 2019
  • Author: Ali H Kanbar, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Common findings and symptoms in patients with Burkitt lymphoma are summarized below.

Abdominal masses, which can cause abdominal pain and distention andascites

Mandibular or maxillary mass

  • Most common presentation in eBL

  • Maxillary tumors are more common (may involve the orbit)

  • Jaw involvement occurs much less frequently (15-20% of sBL cases)

CNS involvement

  • Meningeal infiltration, with or without cranial nerve (CN) involvement (frequently, CN III and CN VII); this is the most common mode of presentation with CNS disease

  • Headaches, visual impairment, and paraplegia from spinal involvement; these may be the initial presenting features in some cases

"B" systemic symptoms

  • B systemic symptoms are uncommon but may be associated with other presenting symptoms, such as fever, weight loss, night sweats, fatigue.

Other

  • Bone marrow involvement is common in Burkitt lymphoma

  • Lymphadenopathy is more common in affected adults than in children


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