What is the US prevalence of Burkitt lymphoma/Burkitt-like lymphoma (BL/BLL)?

Updated: Dec 20, 2019
  • Author: Ali H Kanbar, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

According to the SEER (Surveillance, Epidemiology and End Results) database, the yearly incidence of Burkitt lymphoma/leukemia in the United States across all ages, between 2001 and 2006 was 1759 cases. Most of these cases occurred in patients between ages 20 and 64 years. This disease constituted 0.4% of all lymphoid tumors.

About 30-40% of human immunodeficiency virus (HIV)–related non-Hodgkin lymphoma (NHL) cases are Burkitt lymphoma, and the rate did not seem to decrease with the advent of highly active anti-retroviral therapy (HAART), as Burkitt lymphoma typically affects patients with high CD4 counts (> 200/mm3). [22] This actually suggests that decreased immunity is not a risk factor in this variant of Burkitt lymphoma. (See HIV-1 Associated Opportunistic Neoplasms - CNS Lymphoma.)


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