Which infants are at highest risk of a serious bacterial infection-caused brief resolved unexplained event (BRUE) (apparent life-threatening event) (ALTE)?

Updated: Feb 28, 2019
  • Author: Patrick L Carolan, MD; Chief Editor: Girish D Sharma, MD, FCCP, FAAP  more...
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Zuckerbraun et al (2009) determined that serious bacterial infections (SBIs) occurred in 2.7% of afebrile, well-appearing infants younger than 60 days who experienced an apparent life-threatening event. [14] Infants with a history of prematurity were more likely to have a SBI than infants born at term (6.7% vs 0.8%; P = .04), suggesting the need for added vigilance in screening premature infants for SBI following an apparent life-threatening event.

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