What are the criteria for risk stratification of brief resolved unexplained events (BRUEs) (apparent life-threatening events) (ALTEs)?

Updated: Feb 28, 2019
  • Author: Patrick L Carolan, MD; Chief Editor: Girish D Sharma, MD, FCCP, FAAP  more...
  • Print


The laboratory evaluation of an infant following a brief resolved unexplained event (BRUE) is directed by a thorough history of the event and careful physical examination. Recent BRUE guidelines for evaluation and disposition are now focused on risk stratification. Low risk infants meet the following: age greater than 60 days; gestational age greater than 32 weeks and post-conceptual age greater than 45 weeks, a negative history and normal physical examination; a single BRUE without a "BRUE cluster"; event duration less than one minute; no CPR by a trained provider. Infants meeting these criteria do not need to undergo laboratory testing or imaging studies.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!