Which conditions are associated with brief resolved unexplained events (BRUEs) (apparent life-threatening events) (ALTEs)?

Updated: Feb 28, 2019
  • Author: Patrick L Carolan, MD; Chief Editor: Girish D Sharma, MD, FCCP, FAAP  more...
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Davies and Gupta (2002) conducted a prospective study of infants who presented to an emergency department with an apparent life-threatening event over a 1-year period. [8] The results of this prospective study suggest that a standardized approach to evaluation identifies a specific cause in most presentations. Each infant was subject to a standardized evaluation protocol upon admission; only 23% of patients had no diagnosis after evaluation. The apparent life-threatening events were associated with the following:

  • Gastroesophageal reflux disease - 26%

  • Pertussis - 9%

  • Lower respiratory tract infection - 9%

  • Seizure - 9%

  • Factitious illness including medical child abuse - 3%

  • Miscellaneous - 11%

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