What is the role of PET scanning in the postprocedural follow-up of radiofrequency ablation (RFA) of liver tumors?

Updated: Mar 30, 2021
  • Author: Badar Bin Bilal Shafi, MBBS, MRCP, FRCR, CCT, EBIR; Chief Editor: Kurt E Roberts, MD  more...
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Preliminary results from one study suggested that after RFA in patients with liver metastasis, fluorodeoxyglucose (FDG) PET-CT may detect relapse and treatment failure earlier than multidetector CT (MDCT). [68] In this study, seven cases showed the presence of local recurrence earlier than MDCT.

Initial results of another study showed that PET-CT was significantly better than PET alone for detecting local tumor progression, whereas no significant difference was revealed between MRI and PET-CT. [69] Donckier et al showed in a study of 28 lesions that FDG-PET recognized incomplete tumor ablation earlier than CT did. [70] This study found PET-CT to be accurate in monitoring the efficacy of RFA for treatment of liver metastases.

Further studies in a larger cohort of patients are required to establish the role of PET-CT in patients with liver metastasis who have undergone RFA.

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