What are the risk factors for major complications following percutaneous radiofrequency ablation (RFA) of liver tumors?

Updated: Mar 30, 2021
  • Author: Badar Bin Bilal Shafi, MBBS, MRCP, FRCR, CCT, EBIR; Chief Editor: Kurt E Roberts, MD  more...
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Answer

Many studies have confirmed that RFA is a relatively low-risk procedure with low morbidity and mortality. [46] Few complications are associated with RFA.

Numerous factors are thought to be related to causing major complications, including the following:

  • Tumor size
  • Number of ablation sessions
  • Electrode type (single or cluster)
  • Operator experience

One large study from Italy that included 41 centers showed that an increased number of RF sessions was related to a higher rate of major complications with no significant relation to tumor size or electrode type. [47]


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