What are the FDA guidelines for deferral of blood donation due to medication use?

Updated: Jan 15, 2017
  • Author: Mudassar Zia, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Answer

The FDA has provided guidelines for the deferral of patients who are using some medications. Specific medications and the deferral period for them are as follows:

  • Finasteride and isotretinoin - 1 month from last dose (the rationale behind deferral is the risk to the fetus if the blood is transfused to a pregnant women)

  • Dutasteride - 6 months from last dose (the rationale behind deferral is the risk to the fetus if the blood is transfused to a pregnant women)

  • Acitretin - 3 years from last dose (the rationale behind deferral is the risk to the fetus if the blood is transfused to a pregnant women)

  • Etretinate - Permanent deferral (the rationale behind deferral is the risk to the fetus if the blood is transfused to a pregnant women)

  • Growth hormone from human pituitary glands - Permanent deferral (due to the risk of CJD)

  • Prior use of bovine insulin - Permanent deferral (due to the risk of CJD)

  • Hepatitis B immunoglobulin - Deferral for 12 months (the rationale is that this immunoglobulin is used in cases of exposure to hepatitis B, and since the administration does not prevent the development of hepatitis B infection in all cases, a waiting period of 12 months is recommended before the donor can be screened and deemed fit for donation again.)

  • Clopidogrel - Cannot donate platelets until 14 days after last dose


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