How is transfusion-transmitted cytomegalovirus (CMV) prevented in immunocompromised patients?

Updated: Jan 15, 2017
  • Author: Mudassar Zia, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Answer

The transmission of cytomegalovirus (CMV), which belongs to the herpes group of viruses, is well documented throughout the literature. The organism's transmission is prevented by transfusing leukocyte-depleted blood products, which is consistent with the fact that CMV is a leukocyte-associated pathogen. The organism is a major concern when it comes to transfusing immunocompromised hosts. For this reason, all immunocompromised patients are given CMV-seronegative or leukocyte-depleted blood products. [48, 49, 50, 51]


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