What are the signs and symptoms of transfusion-transmitted bacterial infections (TTBIs)?

Updated: Jan 15, 2017
  • Author: Mudassar Zia, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Although TTBI can produce a wide variety of clinical symptoms (including death), fever (>102º F, or a >3.6º F increase from the pretransfusion baseline), rigors, tachycardia, or an increase in heart rate by more than 40 beats per minute from the baseline and a fall of systolic blood pressure of greater than 30 mm Hg are highly suggestive of the condition. Chills and fever are the most commonly reported symptoms. Other clues include backache, abdominal pain, vomiting, and hypothermia. [1, 2]

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