What is the role of tuberculosis testing in HIV screening during pregnancy?

Updated: Apr 02, 2019
  • Author: Ashley T Peterson, MD; Chief Editor: Ronald M Ramus, MD  more...
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Co-infection with HIV and tuberculosis is very common in developing nations. Immunosuppression from HIV infection contributes not only to a higher rate of tuberculosis reactivation but also to an increased disease severity.

Tuberculosis skin testing should be performed and a 5-mm purified protein derivative (PPD) result interpreted as positive. Alternatively, interferon (IFN)-gamma release assays have been shown to be safe and reliable in pregnancy to screen for latent tuberculosis. [41] If screening test is positive, chest radiography can be performed during pregnancy because radiation risk is exceedingly low.

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