Which age groups have the highest prevalence of macrophage activation syndrome (MAS)?

Updated: Nov 21, 2018
  • Author: Angelo Ravelli, MD; Chief Editor: Lawrence K Jung, MD  more...
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Macrophage activation syndrome generally develops in the earlier phases of the underlying disease or may be the presenting manifestation of SJIA; however, onset has been reported as long as 14 years after the initial diagnosis. [17] In most patients, primary disease is clinically active at the onset of macrophage activation syndrome; however, the syndrome may occasionally occur in a quiescent phase.

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