What is the mortality and morbidity associated with macrophage activation syndrome (MAS)?

Updated: Nov 21, 2018
  • Author: Angelo Ravelli, MD; Chief Editor: Lawrence K Jung, MD  more...
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Macrophage activation syndrome is a complication of rheumatic disease that can follow a rapidly fatal course.

A study by Gormezano et al demonstrated that MAS occur in the majority of childhood systemic lupus erythematosus patients with acute pancreatitis with a higher mortality compared to adult systemic lupus erythematosus patients. [19]

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