What is the global prevalence of macrophage activation syndrome (MAS)?

Updated: Nov 21, 2018
  • Author: Angelo Ravelli, MD; Chief Editor: Lawrence K Jung, MD  more...
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Although considered a rare complication, macrophage activation syndrome is probably more common than previously thought. In a retrospective study from a tertiary care center, 7 of the 103 children (6.7%) diagnosed with SJIA over a 20-year period developed macrophage activation syndrome. [4] Approximately 100 cases have been reported in the literature. [2, 4, 17, 18]

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