When were aeroallergens first recognized as a cause of allergic disease?

Updated: Jul 07, 2019
  • Author: Bhumika Patel, MD; Chief Editor: Michael A Kaliner, MD  more...
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In 1921, R. A. Kern noted that a patient with asthma had a positive prick-puncture skin test to extracts obtained from her mattress. [4] The patient's asthma improved after she enclosed the mattress in heavy packing paper and thoroughly cleaned the room. In 1925, Storm van Leeuwen successfully treated individuals with asthma by moving them to high altitudes or enclosing them in an allergen-proof chamber. [5]

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