What are isolated non-IgG immunoglobulin deficiencies associated with hypogammaglobulinemia?

Updated: Dec 26, 2018
  • Author: Elizabeth A Secord, MD; Chief Editor: Michael A Kaliner, MD  more...
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Answer

Isolated non-IgG immunoglobulin deficiencies (IgM, IgA)

  • IgA deficiency is defined as an absent IgA level with normal IgG and IgM levels in patients older than 4 years in whom other reasons for hypogammaglobulinemia have been ruled out.

  • No molecular or genetic basis for most cases of this disorder is known.


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