Which lab tests may be considered in the workup of hypogammaglobulinemia?

Updated: Dec 26, 2018
  • Author: Elizabeth A Secord, MD; Chief Editor: Michael A Kaliner, MD  more...
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Answer

The following tests may be considered as circumstances warrant:

  • Microarray for DiGeorge (primarily T cell disorder, but T cell disorders will lead to B cell dysfunction if severe) and evaluation for genetic variaqnts of CVID if warranted

  • HIV testing (although untreated HIV is classically assciated with hypergammaglobulinemia, late-stage HIV may be assciated with loss of Immunoglobulin)


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