What is the role of food allergies in the pathophysiology of food-induced pulmonary hemosiderosis (Heiner syndrome)?

Updated: Feb 05, 2020
  • Author: Scott H Sicherer, MD; Chief Editor: Michael A Kaliner, MD  more...
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Answer

This is a rare disorder characterized by recurrent episodes of pneumonia associated with pulmonary infiltrates, hemosiderosis, gastrointestinal blood loss, iron deficiency anemia, and failure to thrive in infants.

While the precise immunologic mechanism is unknown, it is thought to be secondary to a non-IgE hypersensitivity process.


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