What are the histologic findings characteristic of brachioradial pruritus?

Updated: Oct 05, 2020
  • Author: Julianne Mann, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Biopsy of skin reveals atrophy and signs of sun damage, along with reduced numbers of both dermal and epidermal nerve fibers. Evidence exists that this reduction in cutaneous innervation occurs only during symptomatic flares, with innervation normalizing during symptom-free periods; thus, biopsy should ideally be performed when patients are actively experiencing symptoms. [12]


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