Who should undergo complement screening?

Updated: Apr 28, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Michael A Kaliner, MD  more...
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Answer

Complement screening in relatives of patients with complement deficiencies might detect this primary immunodeficiency state and allow prophylaxis to prevent potentially disabling or life-threatening infections. [17]

Complement deficiencies may become apparent in adults by meningococcal and other infections. Adults with N meningitidis infection should be evaluated for a complement deficiency. [22]


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