What are the available doses for epinephrine autoinjector for the emergent treatment of anaphylaxis?

Updated: May 16, 2018
  • Author: S Shahzad Mustafa, MD; Chief Editor: Michael A Kaliner, MD  more...
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An epinephrine autoinjector (eg, EpiPen) for adults is available with a single 0.3-mg (1:1,000 v/v) dose. Similarly, an EpiPen Jr., with a 0.15-mg (1:2,000 v/v) dose, is available for children who weigh less than 30 kg. Auvi-Q comes in similar dosing, and has the advantage of being a more compact device that provides visual and audio cues to help with proper administration.

The Adrenaclick is also available as a single-dose autoinjector of either 0.15 mg or 0.3 mg. The Twinject is a pen-sized device containing 2 doses of epinephrine available either as a 0.15- or 0.3-mg formulation. In both cases, the first of the 2 doses is delivered by autoinjector, and the second is injected manually.

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