What is included in the patient information for epinephrine autoinjector in the treatment of anaphylaxis?

Updated: May 16, 2018
  • Author: S Shahzad Mustafa, MD; Chief Editor: Michael A Kaliner, MD  more...
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Good evidence suggests that physicians underprescribe epinephrine and that patients (or their parents) fail to use epinephrine as quickly as possible. [49, 50, 51] Accordingly, at discharge, all patients should be provided an epinephrine autoinjector and should receive proper instruction on how to self-administer it in case of a subsequent episode. [50]

Patients should be instructed to keep an epinephrine autoinjector with them at all times; they should also carry diphenhydramine and take this in conjunction with use of the epinephrine autoinjector. They should be instructed to keep the device from extremes of temperature. Epinephrine is sensitive to both light and temperature and therefore should not be stored, for example, in a refrigerator or in a motor vehicle glove compartment. They also should be instructed to replace any epinephrine autoinjector before its expiration date.

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