Which medications increase the risk of multiple organ system involvement in anaphylaxis?

Updated: May 16, 2018
  • Author: S Shahzad Mustafa, MD; Chief Editor: Michael A Kaliner, MD  more...
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Answer

A retrospective emergency department study of 302 patients presenting with anaphylaxis, 87 (29%) of whom were taking at least 1 antihypertensive medication, found that antihypertensive pharmacotherapy increased the risk of organ system involvement and hospitalization. [30, 31] There was a more than 2-fold increased risk of involvement in 3 or more organ systems when ACE inhibitors, beta blockers, diuretics, or any antihypertensive medications were used. Most of these agents were also associated with an increased risk for inpatient admission. [30, 31]


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