What are the guidelines for administration of the influenza vaccine in patients with egg allergies?

Updated: May 16, 2018
  • Author: S Shahzad Mustafa, MD; Chief Editor: Michael A Kaliner, MD  more...
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Answer

In the past, a history of IgE-mediated egg allergy has been a contraindication to receiving the annual influenza vaccination. A few years ago, egg-allergic individuals received influenza vaccination, but typically with a graded multi-dose protocol or based on skin prick testing to the vaccine itself. Given a dearth of recent evidence that egg-allergic individuals can safely receive the influenza vaccine with no increased risk of systemic reaction as compared to the general population, the most recent guidelines now recommend that all egg-allergic individuals should be vaccinated with a single dose of influenza vaccine. Furthermore, skin testing has no role because no evidence suggests this reliably identifies individuals at risk of a systemic reaction. [12, 13]


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