What is anaphylaxis?

Updated: May 16, 2018
  • Author: S Shahzad Mustafa, MD; Chief Editor: Michael A Kaliner, MD  more...
  • Print
Answer

Anaphylaxis is an acute, potentially fatal, multiorgan system reaction caused by the release of chemical mediators from mast cells and basophils. [1, 2] The classic form involves prior sensitization to an allergen with later re-exposure, producing symptoms via an immunologic mechanism. (See Pathophysiology and Etiology.)


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!