What is the role of lab studies in the diagnosis of anaphylaxis?

Updated: May 16, 2018
  • Author: S Shahzad Mustafa, MD; Chief Editor: Michael A Kaliner, MD  more...
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Laboratory studies are not usually required and are rarely helpful. However, if the diagnosis is unclear, especially with a recurrent syndrome, or if other diseases need to be excluded, the following laboratory studies may be ordered in specific situations:

  • Serum tryptase may help confirm the diagnosis of anaphylaxis [2] .

  • Urinary 24-hour histamine may help in the diagnosis of recurrent anaphylaxis

  • Urinary 24-hour 5-hydroxyindoleacetic acid levels: If carcinoid syndrome is a consideration

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