What is anaphylaxis?

Updated: May 16, 2018
  • Author: S Shahzad Mustafa, MD; Chief Editor: Michael A Kaliner, MD  more...
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Answer

Anaphylaxis is an acute, potentially fatal, multiorgan system reaction caused by the release of chemical mediators from mast cells and basophils. [1, 2] The classic form involves prior sensitization to an allergen with later reexposure, producing symptoms via an immunologic mechanism.


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