What is the mortality and morbidity associated with alloimmunization from transfusions?

Updated: Sep 08, 2017
  • Author: Douglas Blackall, MD, MPH; Chief Editor: Michael A Kaliner, MD  more...
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Answer

The risk of death from a DHTR is approximately 1 fatality per 3.85 million red blood cell units transfused.

Data regarding the impact of platelet refractoriness on morbidity and mortality for thrombocytopenic patients are inconsistent. However, failure to achieve platelet counts greater than 5 X 109/L significantly increases the probability of life-threatening bleeding.


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