What is the AHA recommended timing for prognostication after return of spontaneous circulation (ROSC) following TTM?

Updated: Sep 15, 2020
  • Author: Catharine A Bon, MD; Chief Editor: Kirsten A Bechtel, MD  more...
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Answer

Answer

The 2015 AHA guidelines note that the timing for prognostication is typically 4.5-5 days after ROSC for patients treated with TTM, in order to minimize false-positive results due to a drug-induced depression of neurologic function. However, the guidelines acknowledge that withdrawal of life support may occur before 72 hours because of underlying terminal disease, brain herniation, or other clearly nonsurvivable situations. [43]


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