What is the role of lab tests in the workup of axillary hyperhidrosis?

Updated: Feb 12, 2019
  • Author: Richard H S Karpinski, MD, FACS; Chief Editor: Gregory Gary Caputy, MD, PhD, FICS  more...
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Diagnosis of axillary hyperhidrosis is essentially from patient history (see Clinical) and from visible signs of excessive sweating. No useful formal staging or severity scale exists, but the terms mild, moderate, and severe are used in some clinical descriptions. Hund et al have proposed a quantitative definition of axillary hyperhidrosis, but the requirement of a gravimetric assay makes this approach practical only in the research setting.

Laboratory testing may play a vital role in excluding secondary hyperhidrosis from causes such as hyperthyroidism, pheochromocytoma, carcinoid or other malignancy, tuberculosis, or adrenal pathology, especially in patients with asymmetric, late, or atypical onset of symptoms.

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