What is the prevalence of angiosarcoma of the scalp?

Updated: Jan 03, 2020
  • Author: Jonathan S Zager, MD, FACS; Chief Editor: Gregory Gary Caputy, MD, PhD, FICS  more...
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This disease is primarily located on the head and neck of elderly males. In one of the largest series to date, Perez et al reported on 88 patients with cutaneous angiosarcoma divided into 4 groups: 38 head and neck, 30 radiotherapy-induced, 13 sporadic trunk/extremity, and 7 Stewart-Treves syndrome related. The median age at diagnosis for the entire cohort was 70 years (72.5 y for head and neck), with 95% being white. Of those with head and neck angiosarcoma, 82% were male. Wilson-Jones first distinguished a unique form of angiosarcoma developing in the face and scalp of elderly individuals, noting that it carries a relatively poorer prognosis than the other forms. This form of angiosarcoma is also known as senile angiosarcoma or malignant angioendothelioma. Currently, angiosarcoma of the face and scalp in elderly patients is recognized as a distinctive subgroup. The estimated ratio of male-to-female predominance is approximately 3:1.

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