What are the treatment options for pyoderma gangrenosum?

Updated: Jan 30, 2020
  • Author: Ginard I Henry, MD; Chief Editor: Gregory Gary Caputy, MD, PhD, FICS  more...
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Topical antimicrobials and those with systemic effects are effective to some degree in controlling the disease. The mainstay of management appears to be anti-inflammatory regimens of steroids with local and systemic effect, as well as steroid-sparing regiments such as cyclosporine or azathioprine. Surgical caveats remain minimal debridement and limitation of all forms of skin trauma and irritation. The slightest cutaneous injury may evolve into a disastrous area of necrosis.

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