What is the clinical course of neurofibromatosis?

Updated: Jan 30, 2020
  • Author: Ginard I Henry, MD; Chief Editor: Gregory Gary Caputy, MD, PhD, FICS  more...
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Clinical course is difficult to predict. However, to the plastic surgeon, the most significant manifestations of the disease are the multiple and varied facial deformities. The therapeutic plan essentially involves excising the lesions that are bothersome or visible. Occasionally, only palliative partial resection can be accomplished. Bony involvement of the facial skeleton also creates a difficult problem. Total satisfactory excision of all symptomatic lesions is seldom accomplished.

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