What is a trichilemmoma?

Updated: Jan 30, 2020
  • Author: Ginard I Henry, MD; Chief Editor: Gregory Gary Caputy, MD, PhD, FICS  more...
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Trichilemmoma is a benign tumor with a pattern of globular glycogen-rich clear cells. Occasionally, keratinization in the center is identified grossly. Trichilemmommas can be related to Cowden disease, a multiple hamartoma syndrome with papillomas of the oral mucosa, acrokeratoses, and, most significantly, malignant tumors of the breast, thyroid, and GI tract. Additionally, a rare carcinoma variant of trichilemmoma is known as trichilemmal carcinoma.

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