How is a trichoepithelioma characterized?

Updated: Jan 30, 2020
  • Author: Ginard I Henry, MD; Chief Editor: Gregory Gary Caputy, MD, PhD, FICS  more...
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Answer

Answer

This tumor is characterized by collections of basal cells that are similar to the hair bulb. It is also remarkable for the presence of numerous horn cysts. Both of these tend to be accompanied by an inflammatory stroma that is fibrous. Occasional calcifications and melanin granules also can be found. The abortive hair shafts and follicles are another characteristic of trichoepithelioma. Occasionally, a differential diagnosis from a basal cell carcinoma can be difficult to determine. The most significant distinguishing features are a papillary frondlike orientation of basaloid cells and epithelial tracts consisting of more than one layer of basaloid cells.


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