What are the histologic characteristics of schwannomas?

Updated: Jan 30, 2020
  • Author: Ginard I Henry, MD; Chief Editor: Gregory Gary Caputy, MD, PhD, FICS  more...
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Answer

Answer

Histologically, schwannomas are rounded and encapsulated. They are mostly characterized by the presence of plump S-shaped spindle cells and myxoid stroma. The spindle cells show marked tendency to palisading and irregular configuration, with stellate cells also present in the myxoid stroma. The lesions are also populated with chronic inflammatory cells and hyalinized blood vessels.


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