What are the treatment options for seborrheic keratosis (SK)?

Updated: Jan 30, 2020
  • Author: Ginard I Henry, MD; Chief Editor: Gregory Gary Caputy, MD, PhD, FICS  more...
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Most patients require no specific treatment for seborrheic keratosis. Close patient surveillance and annual clinical evaluations are recommended. For removal, curettage and cryoablation are the most common treatments. However, clinical trials have indicated that a 40% hydrogen peroxide topical solution is an effective alternative to surgery in the treatment of seborrheic keratosis, especially with regard to facial keratoses, showing better results on the Physician’s Lesion Assessment scale than did the administration of vehicle. [16, 17]

Rarely, malignant lesions (eg, Bowen disease) can arise within seborrheic keratoses or malignancies, such as melanoma, can mimic the appearance of a seborrheic keratosis. When malignancy is suspected or diagnosis is indeterminate, an excision biopsy is required. Withhold wide local excision until malignancy is confirmed.

Go to Seborrheic Keratosis for complete information on this topic.

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