What are the ETA treatment guidelines for amiodarone-associated thyroid dysfunction?

Updated: Aug 28, 2020
  • Author: Mini Gopalan, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
  • Print

In 2018, the European Thyroid Association published guidelines concerning amiodarone-related thyroid dysfunction management. Recommendations include the following [16] :

  • Patients with amiodarone-induced thyrotoxicosis (AIT) should be considered at risk of an emergency treatment at any time due to the increased mortality and morbidity, particularly in the elderly and/or if a reduced left ventricular dysfunction is present
  • Antithyroid drugs are recommended as the medical treatment of choice for most cases of AIT 1
  • Oral glucocorticoids are recommended as the first-line treatment for AIT 2 with moderate to severe thyrotoxicosis; the decision to treat milder or subclinical forms should take into account the underlying cardiac conditions, with a close interaction with the specialist cardiologist
  • Ablation of a hyperfunctioning thyroid gland with an elective thyroidectomy or radioiodine treatment, as in other forms of spontaneous hyperthyroidism, is recommended

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!