What is the role of imaging studies in the diagnosis of amiodarone-associated thyroid dysfunction?

Updated: Aug 28, 2020
  • Author: Mini Gopalan, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

Although the above lab studies can confirm a diagnosis of thyrotoxicosis, further studies are necessary to recognize the correct type of AIT. [6] This distinction is important when choosing treatment modalities.

  • An ultrasonogram of the thyroid that shows abnormalities such as hypoechoic or nodular patterns or increased gland size is more indicative of type 1.

  • Radioactive iodine uptake studies are not helpful in the United States. Normal or elevated values found in radioactive iodine uptake studies suggest type 1 AIT, but this is rarely seen in the United States. The high levels of iodine result in serum levels that compete with the tracer used to perform the uptake test; thus, test results of type 1 and type 2 usually have uptakes of less than 1%. Detectable 24-hour radioactive iodine uptake is seen in tests of most patients with AIH. This may be caused by excess stimulation of the thyroid by TSH.


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