Which blood tests are performed in the workup of organ transplantation-related osteoporosis?

Updated: Jul 02, 2020
  • Author: Carmel M Fratianni, MD, FACE; Chief Editor: George T Griffing, MD  more...
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Answer

Because even patients with entirely normal pretransplant BMD experience fractures following solid organ transplantation, it is not possible to reliably predict who will sustain a fracture. Thus, it has been recommended that all transplant candidates undergo an evaluation of bone health. [69] The following laboratory studies are indicated in the pretransplant evaluation of all patients awaiting solid organs [2, 3] :

  • Serum calcium level

  • Phosphorus level

  • Bicarbonate level

  • Alkaline phosphatase level

  • BUN/creatinine levels

  • Intact PTH assay, to assess for hyperparathyroidism (primary or secondary)

  • 25-Hydroxyvitamin D value to assess total body vitamin D stores

  • Thyroid function tests (eg, thyroid-stimulating hormone, free levothyroxine)

  • Testosterone level (males only), to ensure eugonadism

  • Estradiol and FSH levels (in females with amenorrhea or irregular cycles)

  • Magnesium level


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