Which patients are at highest risk for organ transplantation-related osteoporosis?

Updated: Jul 02, 2020
  • Author: Carmel M Fratianni, MD, FACE; Chief Editor: George T Griffing, MD  more...
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Answer

Answer

Kidney transplant patients generally experience less transplant-related bone disease than cardiac [15] (50% vertebral fracture prevalence), lung, or liver transplant patients. This may be because renal transplant recipients are younger (on average) at the time of transplantation and may have better management and recognition of metabolic bone disease prior to transplantation; moreover, they may receive lower doses of immunosuppression overall.

Kidney transplant patients with type 1 diabetes mellitus and SPKT recipients are probably an exception to this general statement because, for the reasons outlined above, they are predisposed by their type 1 diabetes to cortical osteopenia.


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