How is organ transplantation-related osteoporosis treated?

Updated: Jul 02, 2020
  • Author: Carmel M Fratianni, MD, FACE; Chief Editor: George T Griffing, MD  more...
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Answer

Answer

Administer vitamin D at 400-1000 IU/d to all patients. Advise patients to maintain an adequate total elemental calcium intake (ie, 1000-1500 mg) and to take supplements as necessary.

Any patient who meets World Health Organization (WHO) criteria for low bone mass (osteoporosis) should receive pharmacologic treatment similar to any other patient with osteoporosis or osteopenia.

Patients should avoid cigarette smoking and heavy alcohol consumption, both of which are associated with a negative bone balance. Adequate nutrition is essential for optimal bone health in transplant recipients. Regular weight-bearing and muscle-strengthening exercises are recommended to reduce the risk of fracture as first-line therapy for osteoporosis.


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