What are the signs and symptoms of organ transplantation-related osteoporosis?

Updated: Jul 02, 2020
  • Author: Carmel M Fratianni, MD, FACE; Chief Editor: George T Griffing, MD  more...
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Answer

Answer

The following findings should be noted during the physical examination:

  • Loss of height or kyphosis, which could suggest occult compression fracture
  • Blue sclerae, which suggest underlying osteogenesis imperfecta
  • Bone tenderness or pain, which could suggest occult fracture, avascular necrosis, or osteomalacia
  • Incapacitating pain or tenderness in the lower extremities or bones of the feet following organ transplantation, which could suggest the calcineurin-inhibitor–induced pain syndrome

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