What are the failure rates in sentinel lymph node (SLN) biopsy mapping of breast cancer?

Updated: Feb 13, 2019
  • Author: Mary Jo Wright, MD; Chief Editor: James Neal Long, MD, FACS  more...
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Most groups would agree that success in SLN mapping improves with surgeon experience. In their initial series, Krag et al demonstrated a mapping failure rate of 18% with the solitary use of radiocolloid and a failure rate of 35% based on the solitary use of blue dye. [21] Subsequent reports by Giuliano have demonstrated a failure rate of 5%. [22] In the initial series by Cox et al, a failure rate of 6.6% was noted with a combination technique, [23] which subsequently decreased to 5% in a later study. [24]

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