What are the rates of miscarriage in women with gestational diabetes mellitus (GDM)?

Updated: Apr 29, 2020
  • Author: Thomas R Moore, MD; Chief Editor: George T Griffing, MD  more...
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Answer

Answer

In all women with preexisting diabetes mellitus, there is a 9-14% rate of miscarriage. Current data suggest a strong association between the degree of glycemic control before pregnancy and the miscarriage rate. Suboptimal glycemic control has been shown to double the miscarriage rate in women with diabetes. A correlation also exists between more advanced diabetes and miscarriage rates. Patients with long-standing (>10 y) and poorly controlled diabetes (glycohemoglobin exceeding 11%) have been shown to have a miscarriage rate of up to 44%. Conversely, excellent glycemic control normalizes the miscarriage rate.


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