What is the prognosis of secondary hyperparathyroidism?

Updated: Dec 24, 2020
  • Author: Lawrence T Kim, MD, FACS, FACE; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Medical treatment of secondary hyperparathyroidism is successful in most patients. Patients who require parathyroidectomy have approximately a 10% risk of recurrent or persistent disease. This may be due to a hyperfunctioning or missed neck gland or hyperplasia of the autograft. Occasionally, a patient has persistent hypoparathyroidism after operation. If tissue has been cryopreserved, transplantation may reverse hypoparathyroidism. If hypoparathyroidism is permanent, lifelong calcium and calcitriol supplementation is necessary.

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