What are the signs and symptoms of secondary hyperparathyroidism?

Updated: Dec 24, 2020
  • Author: Lawrence Kim, MD, FACS, FACE; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Because virtually all patients with CKD have hyperparathyroidism to some degree, there is not a unique clinical presentation that is a hallmark of secondary hyperparathyroidism. Often, secondary hyperparathyroidism is discovered on routine laboratory testing when monitoring individuals with CKD. In patients with secondary hyperparathyroidism due to vitamin D deficiency, the symptoms result mainly from the vitamin deficiency (and include increased fracture risk in osteomalacia, and, rarely, myopathy). In advanced cases of secondary hyperparathyroidism, some patients may have bone pain.

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